SEDATION SLEEP AID

Lactoferrin, a protein in your body that fights infection, including those caused by bacteria and viruses. The enteric environment and sleep quality have been reported to be improved by lactoferrin. Taking lactoferrin for four weeks may improve subjective sleepiness, fatigue on rising, nighttime sleep quality, depressed mood, and stool consistency. Lactoferrin helps regulate iron absorption from the intestine into the body.+(1)(2)

In men and women who took CLOCK®, a proprietary blend of Rosemary (Rosmarinus officinalis) and Daylily (Hemerocallis fulva) extracts before bedtime, several key factors supporting cognitive brain function were significantly enhanced.+(3) 

A dose of CLOCK® significantly increased plasma levels of BDNF, a protein crucial to brain health. Additionally, irisin and melatonin levels increased, as did acetylcholine (Ach) levels. There was an improvement in attentiveness, alertness, focus, feeling energetic, enthusiasm, feeling well rested, with a reduction in feeling sluggish and feeling depressed without the same improvement in the placebo group.+

Brain-derived neurotrophic factor (BDNF) is an important neurotrophin that circulates in plasma and affects major areas of the central nervous system. It is involved in various neuronal systems as well as neuronal plasticity. It has been shown that increasing levels improve mood and support cognitive function. CLOCK increases brain-derived neurotrophic factor (BDNF), which may improve cognitive performance. +(4)

The CLOCK product helps maintain circadian rhythm balance. As compared to control cells, CLOCK® significantly increased expression of Clock (circadian locomotor output cycles kaput), Bmal1 (brain and muscle Arnt-like protein 1), Sirt (Sirtuin 1), and F-box and leucine-rich repeat protein 21 (Fbxl21) and Fbxl3.+

In two double-blind human studies, CLOCK significantly increased plasma melatonin, a biomarker of circadian dysregulation.+

Clocks Core Benefits

- Increases BDNF, a protein, and irisin, a hormone which improves mood and cognitive function.+

- Low levels of melatonin are associated with sleep problems. Melatonin, the sleep hormone, is increased by CLOCK® to promote better sleep.+

- Enhance alertness, focus, and energy by activating key nootropic biomarkers.+

- We lose our levels of BDNF, acetylcholine, choline, irisin, and melatonin as we age. CLOCK may promote the aging process by elevating these key biomarkers.+

- CLOCK's positive effects on clock genes may help the body regain synchronization with the master clock, so you can enjoy life more.+

- Weekend warriors and athletes will benefit from CLOCK. After taking it, the body and mind may feel refreshed, uplifted, and energetic.+

- CLOCK has been linked to increased muscle mass, strength, and metabolism with increased irisin levels.+

Studies have shown that oligonol supports healthy blood glucose and lipid levels after meals, reduces visceral fat, decreases wrinkles and brown spots on the skin, and improves endurance. +

A patented, low-molecular-weight polyphenolic extract derived from lychee fruit (85%) and green tea (15%), Oligonol provides excellent absorption and numerous anti-aging benefits. Age is primarily caused by inflammation, oxidative stress, and poor blood circulation. +(5)(6)

It is also possible that oligonol reduces fine lines on the face. Some deep wrinkles and sleep wrinkles were reduced. Following the use of Oligonol, the level of CRP decreased.+

Melatonin is a hormone produced by your pineal gland. By regulating your circadian rhythm, it manages your natural sleep cycle. Insomnia is often treated with it as a sleep aid. In addition to improving sleep, melatonin also manages immune function, blood pressure, and cortisol levels. In addition, some studies suggest that it can significantly improve various health conditions as an antioxidant. Studies have shown that melatonin improves eye health, reduces symptoms of seasonal depression, and even relieves acid reflux. +(7)(8)

The sleep hormone melatonin is often called the sleep hormone for a good reason. Insomnia can be treated with this natural remedy, and it's one of the most popular sleep aids. Melatonin is effective in supporting better sleep in multiple studies. Researchers found that taking melatonin two hours before bed helped people fall asleep faster and improved their sleep quality. In a large analysis of 19 studies in children and adults with sleep disorders, melatonin improved sleep quality and reduced the time it took to fall asleep. +(9)(10)

Growth and regeneration of cells are essential functions of human growth hormone (HGH). Strength and muscle mass have also been associated with higher levels of this important hormone. Men may benefit from supplementing with melatonin to increase levels of HGH. It was found that both low (0.5 mg) and high (5 mg) doses of melatonin were effective at increasing HGH levels in eight men in a small study. +(11)(12)(13)